Platelets Rich Fibrin (PRF) Injections at PureMargins Aesthetic Clinic
Natural Skin Rejuvenation.
Accelerated Healing.
Enhanced Collagen Production.
What Our Clients Say
EXCELLENT Based on 6 reviews Georgiana T2023-10-08Trustindex verifies that the original source of the review is Google. Irina is great at what she is doing. I had already 2 PRF/micro needling treatments completed by Irina and she took the time to explain the whole process in detail giving me the chance to ask questions and making sure that she answered to the best of her knowledge. She is gentle but strong and she is doing her best to make you feel comfortable. I love how my skin felt and looked after the treatments and I always can’t wait to go back. I recommend Irina too all my friends and encouraged them to go to her because the results are awesome and I feel my skin rejuvenated and glowing. a kohn2023-09-14Trustindex verifies that the original source of the review is Google. First time receiving an IV wellness drip for my husband and I. The experience was phenomenal. I am in the medical field and I found Irina‘s professionalism and knowledge to be stellar. Thank you Irina! I’ll see you in 2 weeks. Paul Csabai2023-08-05Trustindex verifies that the original source of the review is Google. Vamp Facial Larissa Csiffari2023-07-11Trustindex verifies that the original source of the review is Google. Irina is the best, she made me feel confident from the moment I walked in and was very patient when explaining the treatments and what was best for my skin. She gave me a lot of confidence in choosing the right treatments, and made me look exactly how I pictured myself. The microneedling with blood plasma treatments are a must have and worth every penny. I am in my fourth session now, and my skin really shows a difference in skin tightness and texture without any makeup. Will definitely be returning! Great prices, and the results won’t let you down. Debra Rogers2023-07-11Trustindex verifies that the original source of the review is Google. Irina is an amazing nurse! She offered me a free consultation and took all her time to answer all my questions! I highly recommend going to see Irina! Kristen Chellson2023-05-18Trustindex verifies that the original source of the review is Google. Irina is very knowledgeable, kind, intelligent and truly includes you in the treatments. It was literally painless, I had no bruising and so natural. I will be going back to her.
Benefits of PRF Treatment at PureMargins Aesthetic Clinic
Looking for a regenerative skin-boost that is as safe as it is sophisticated? At PureMargins Aesthetic Clinic in Northbrook, Irina Marginean, APRN, FNP-BC, delivers the gold-standard in PRF Chicago care. By drawing a small sample of your blood, spinning it into growth-factor–rich serum, and re-injecting it precisely where you need rejuvenation, Irina harnesses the body’s own healing power.
Bright, Rested Eyes with Zero Concealer
Our signature PRF under eyes Chicago protocol channels concentrated growth factors directly into the tear-trough. Because PRF under eyes releases platelets over days, you’ll see darkness fade, hollows fill, and crepey skin tighten naturally. The treatment doubles as an ultra-gentle PRF eye treatment, so even sensitive lids tolerate it well—and if you’ve been Googling under eye PRF near me, you’ll appreciate having world-class care minutes from home.
Smile Without the Lines
Laughter is beautiful; deep creases are optional. PRF smile lines therapy delivers a soft fibrin scaffold beneath nasolabial folds. As new collagen weaves through the matrix, folds flatten gradually—so friends notice a fresher you, not a “filled” look. The result is a pliable, youthful cushion that moves naturally with every grin.
Whole-Face Collagen Rebuild
A custom series of PRF for face injections acts like a slow-release fertilizer for skin, steadily boosting firmness in cheeks, temples, and jaw. Paired with a glow-inducing PRF facial or staged PRF facial treatment, this approach tightens laxity, shrinks pores, and restores harmonious contours—giving you the selfie-ready luminosity usually reserved for photo filters.
Fully Natural, Autologous Science
Unlike synthetic fillers, PRF is made from your own blood. These pure Platelet Rich Fibrin Injections carry no foreign chemicals, so risk of allergy is virtually nil. The fibrin mesh integrates smoothly, stimulates true tissue regeneration, and biodegrades only after its work is done—leaving new collagen in its place.
Silky-Smooth Texture & Glass-Skin Glow
Each PRF skin treatment awakens dormant fibroblasts, increasing elastin, hyaluronic acid, and micro-circulation. Over weeks, rough patches soften, fine lines blur, and that coveted “lit-from-within” sheen emerges. Clients rave about the baby-soft finish and long-lasting PRF skin radiance that even highlighter can’t fake.
Results That Unfold Gracefully
A single PRF treatment starts a months-long cascade of renewal. Because platelets are released slowly from the fibrin clot, improvements appear subtly—making it easy to keep your enhancement a personal secret while still enjoying steadily brighter, bouncier skin.
Convenient Care, Minimal Downtime
With micro-cannula delivery, swelling and puncture marks are tiny, letting most clients return to work the same day. If “lunchtime refresh” tops your wish list, our easy-access location satisfies every search for PRF injections near me—complete with free parking and evening appointments.
Versatile Protocols Tailored to You
From single-zone boosts to full-face makeovers, Irina curates layered PRF treatments or combination PRF Therapy plans that match your goals, budget, and calendar. Mix with microneedling, combine with laser, or stack sessions quarterly—the flexibility makes long-term beauty maintenance straightforward.
Safe Precision in Delicate Areas
The orbital region demands accuracy, and our ultrasound-guided technique places PRF under eye deposits exactly where they belong, avoiding vessels and nerves. This precision not only bumps up safety but also extends the longevity of your under-eye rejuvenation.
Trusted Expertise at a Chicago-Area Destination
As a board-certified nurse practitioner, Irina pairs medical rigor with an artist’s touch, making PRF Chicago synonymous with honest, evidence-based results. Transparent pricing, thorough follow-up, and concierge-level care turn first-time visitors into lifelong devotees eager to share their renewed confidence.
Ready to reclaim rested eyes, a smoother grin, and luminous skin? Book your consultation today and discover why PureMargins is the trusted home of PRF under eyes Chicago excellence—your neighborhood destination for science-backed beauty.

What is PRF?
Platelet-Rich Fibrin (PRF) is a next-generation form of your own plasma. During Platelet Rich Fibrin Injections, a small tube of blood is spun without anticoagulants, creating a soft fibrin matrix loaded with platelets, white cells, and stem-cell messengers. When that “liquid scaffold” is re-introduced to precise areas of skin, it behaves like a time-release capsule—feeding the tissue natural growth factors for weeks instead of minutes.
Unlike earlier platelet concentrates, PRF Therapy contains no chemicals, so it integrates seamlessly while coaxing collagen, elastin, and new micro-vessels. That makes it an ideal PRF skin treatment for anyone who wants smoother texture and firmer tone without synthetic fillers or extended downtime: just a quick draw, a gentle reinjection, and you’re free to glow.
Patients choose our Northbrook studio for PRF Chicago sessions because each procedure is artistically mapped—whether you’re booking a mid-face boost, an under-eye refresh, or a complete PRF facial. The result? Subtle, steady rejuvenation that looks like vacation-rested skin, not work done. Ready to see what your own biology can do? We’re here to guide you, start to finish.
Step-by-Step of PRF Skin at PureMargins Aesthetic Clinic
Re-energize your complexion the natural way. At PureMargins Aesthetic Clinic—just north of the city—Irina Marginean, APRN, FNP-BC, delivers the gold-standard in PRF Chicago care. By transforming a tiny blood draw into concentrated growth factors, she turns everyday plasma into skin-loving medicine. These refined Platelet Rich Fibrin Injections replace harsh chemicals with your own biology, so results feel authentic—and look it, too.
Step 1 – Personal Consultation & Skin Mapping
Irina begins with a deep-dive assessment—examining tone, laxity, lifestyle, and goals. Together you choose the best form of PRF Therapy for you, pinpointing priority zones (eyes, mid-face, smile folds) and setting realistic timelines so you know exactly when to expect results.
Step 2 – Gentle Blood Draw & PRF Processing
A single vial is collected, then spun in a specialized centrifuge that skips all anticoagulants. This creates a straw-gold fibrin matrix rich in platelets—your personal elixir for collagen renewal. In just ten minutes, the serum is ready for precise PRF facial artistry.
Step 3 – Comfort-Focused Numbing & Sterile Prep
While your concentrate forms, a light topical anesthetic eases any potential sting. Skin is cleansed and cooled to ensure an ultra-clean canvas, setting the stage for seamless PRF facial treatment delivery and minimal post-procedure redness.
Step 4 – Precision Micro-Cannula Placement
Using a flexible, blunt-tip cannula, Irina layers PRF exactly where your face needs structural support—under the eyes to brighten (PRF under eyes) or along folds to soften PRF smile lines. This technique minimizes bruising and places growth factors right at the collagen factories.
Step 5 – Soothing Finish & Same-Day Return to Life
A cool mask and antioxidant serum calm the skin; any pinkness typically fades by evening. Many clients book over lunch because the treatment doubles as an instant “glass-skin” refresher for the entire PRF for face zone—no downtime, all glow.
Step 6 – Collagen-Building Follow-Up & Future Boosts
Over the next 6–8 weeks, platelets release growth factors in waves, steadily firming and brightening. Your follow-up visit lets Irina chart progress and, if desired, schedule maintenance PRF treatments—ideal for anyone who typed “PRF injections near me” and wants effortless, ongoing results close to home.
From the first consult to the last compliment, our PRF Chicago protocol is designed to make glowing skin feel effortless—and entirely, beautifully yours. Book today to reserve your spot.
15% OFF YOUR FIRST APPOINTMENT & FREE CONSULTATION
Treatment Areas & Goals
- Under-Eye
- Smile-Lines
- Mid-Face & Cheeks
- Temple Hollow
- Jawline & Chin
- Neck & Décolletage
The thinnest skin on your face is also the first to show dark circles and hollows. During a PRF under eye session, Irina draws a tiny vial of blood, spins it, then threads the straw-gold serum along the orbital rim with a single flexible cannula. Because this PRF eye treatment releases growth factors for weeks, collagen thickens gradually, brightening pigment and firming crepey texture with zero “filler-puff.”
An interesting twist: our technique fans the fibrin into a gentle hammock that also boosts micro-circulation. Many clients notice their concealer use drop by half within a month, and the refreshed look lasts long after vacation tans have faded.
Deep parentheses around the mouth form where skin folds with every laugh. Instead of stuffing the crease with heavy gel, PRF smile lines therapy lays a living mesh just above the muscle. Over 6–8 weeks, fibroblasts weave new collagen through that scaffold, lifting the fold from beneath while keeping your grin completely natural.
A single entry point at the cheek allows linear-threading passes, minimizing bruises. Patients love that the fold softens gradually; friends see the glow but never guess you had work done.
Flattened cheeks can make the whole face look tired. A bespoke PRF facial treatment places micro-columns of fibrin over the cheekbone and into deep fat pads, restoring the youthful “OG curve” that bounces light upward. Because Platelet Rich Fibrin Injections also improve tiny blood vessels, skin overlying the area takes on a peachy flush that makeup can’t fake.
Irina often pairs these cheek boosters with light microneedling, pushing the same serum superficially for an all-over glass-skin glow—a true PRF for face upgrade in a single visit.
Sunken temples can create a skeletal look and flatten the outer brow. By layering PRF along the temporal fossa, Irina restores support to the lateral eye and subtly lifts the brow tail. Only two cannula passes are needed, and the area’s rich blood supply speeds healing, so most clients who searched “PRF injections near me” are back to workouts the next morning.
Fun fact: temple filling with PRF often reduces tension headaches because the fibrin cushions superficial arteries, decreasing pulsation against the bone.
Blunting along the mandible can blur the once-crisp edge between face and neck. Strategic PRF treatments dot growth-factor-rich fibrin along the jaw angle and prejowl sulcus, coaxing bone-like collagen that firms the lower face. Over time, skin tightens and the chin projects subtly forward, sharpening profile photos without implants or threads.
Because PRF integrates with your own tissue, the jawline upgrades stay supple—you can still feel every laugh and sip, just with a more sculpted finish.
Perfume spots and V-necklines reveal sun damage long before the cheeks do. A silky PRF skin treatment combines microneedling with superficial fibrin injections across the neck and chest, flooding thin dermis with platelets that repair UV-crumbled collagen. Fine “necklace lines” smooth, and crepey cleavage skin regains bounce.
Clients routinely report that lotions absorb better, makeup pills less, and the area matches the youthfulness of a freshly treated face—proof that PRF Therapy isn’t just for cheeks and eyes.

Why Should You Book
1
Expert Care
At PureMargins Aesthetics Clinic, treatments are administered by Irina Marginean, APRN, FNP-BC, who brings a high level of expertise and years of experience in aesthetic medicine. Her detailed understanding of facial anatomy and mastery in regenerative techniques like PRF ensure safe procedures and personalized care.
2
Naturtal Treatments
PureMargins Aesthetics Clinic prioritizes innovative, effective treatments that harness natural processes, such as PRF, to enhance your appearance. This approach minimizes the risk of allergic reactions and provides more sustainable and natural-looking results compared to traditional synthetic treatments.
3
Tailored Solutions
Every treatment at PureMargins is customized to meet the unique needs and goals of each patient. Whether you’re looking to rejuvenate your skin, stimulate hair growth, or enhance facial volume, our clinic provides a detailed consultation and personalized plan to ensure optimal outcomes that reflect your individual aesthetic aspirations.
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PRF Preparation
- Hydrate, Hydrate, Hydrate
Arrive well-watered—two extra glasses of water both the night before and the morning of your appointment boost plasma volume, giving PRF Therapy an even richer platelet yield for better results.
- Pause Blood-Thinners & Herbal Extras
For seven days, avoid aspirin, ibuprofen, fish oil, garlic, and ginkgo; they can thin blood and heighten bruising after Platelet Rich Fibrin Injections. If you take prescription anticoagulants, check with your primary doctor first.
- Feed Your Platelets
Lean meats, leafy greens, berries, and a vitamin-C boost help platelets function optimally. Arriving nourished supports collagen-building after your PRF skin treatment, so the glow lasts longer.
- Dial Down Alcohol & Heavy Workouts
Skip cocktails and intense gym sessions 24 hours pre-visit; reduced vascular dilation means less swelling and quicker recovery from your PRF facial. Gentle stretching or a walk is fine.
- Plan Your Calendar & Photos
Most clients can return to work immediately, but minor redness can linger for a day. Snap your own “before” pictures, then compare in two weeks—it’s rewarding to see why PRF Chicago is a favorite search for natural, progressive results (and it helps Irina fine-tune future sessions).
PRF Aftercare
- Hands Off & Gentle Cleanse
For the first 12 hours, resist the urge to touch or wash the treated skin; after that, use a mild, fragrance-free cleanser morning and night. This is especially important around the delicate PRF under eye zone, where freshly placed growth factors need quiet time to settle before they can start rebuilding collagen. - Hydrate Inside and Out
Keep drinking plenty of water and add a protein-rich snack (think Greek yogurt or a lean-meat lunch) to fuel tissue repair. A lightweight hyaluronic serum will amplify the dewy look you left the clinic with—perfect for showcasing that post-treatment PRF skin luminosity. - Sun-Smart Protection
New collagen is photosensitive, so apply a broad-spectrum SPF 50 every morning and reapply if you’re outdoors longer than two hours. A wide-brim hat adds extra insurance, helping your PRF facial results last longer and preventing pigment from creeping back into the under-eye or smile-line areas. - Skip Sweat & Makeup for 24 Hours
Heavy workouts, saunas, and full-coverage foundations can all introduce bacteria or excess heat while micro-channels are still closing. Give your skin a day of rest; by tomorrow you can return to Pilates—just remember to cleanse gently afterward to protect those freshly placed Platelet Rich Fibrin Injections.
- Plan Your Follow-Up and Support Skin Health
Collagen production peaks around the six-week mark, so book your next visit before you leave the clinic. Consistent, spaced-out PRF treatments build on each other, turning an initial boost into long-term firmness. In the meantime, a nightly antioxidant cream keeps the regeneration cycle humming between appointments.
Frequently Asked Questions
A PRF treatment turns your own plasma into Platelet Rich Fibrin Injections that act as a time-release “liquid scaffold.” This 100 % autologous process—often called PRF Therapy—feeds skin growth factors for weeks, rebuilding collagen without synthetic fillers.
Single-zone pricing for PRF Chicago sessions starts at $300. Your exact fee depends on how many tubes of fibrin you need and whether we combine zones during one visit.
Results from one PRF skin treatment build for 6–8 weeks and can glow for 9–12 months. Many clients book twice-yearly PRF treatments to keep fresh collagen cycling and maintain that healthy PRF skin finish.
Yes. Because PRF under eyes uses only your plasma, it’s gentle enough for the tear-trough. The fibrin thickens thin skin, lifts hollows, and improves micro-circulation, steadily brightening shadows with virtually no risk.
Absolutely. Instead of stuffing the crease, we layer fibrin beneath it. New collagen weaves through the scaffold over weeks, smoothing the fold while keeping your smile completely natural.
PureMargins sits just off I-294 in Northbrook. Online scheduling lets you reserve evenings or Saturdays, and our front desk can secure the soonest slot for the zone you want—whether that’s cheeks or PRF under eye brightening.
PRF spins more slowly than PRP, capturing extra white cells and fibrin. A PRF facial uses microneedling to bathe the surface in growth factors, while a PRF facial treatment adds targeted injections for lift and volume—results last longer than classic PRP.
Expect firmer cheeks, refined pores, and a gentle lift along the jaw. Because PRF also boosts micro-vessels, tone warms up with a healthy flush makeup can’t fake.
After topical numbing, Irina threads a blunt micro-cannula from one tiny entry point, fanning serum beneath the orbital rim. Most clients feel light pressure; tenderness fades within hours.
Anyone with active infection, uncontrolled autoimmune disease, or a serious blood disorder should delay PRF for face until cleared by their physician. A thorough health review ensures every procedure is as safe as it is effective.
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